Our Story

In May 2017, the WIRB-Copernicus Group (WCG) brought together two outstanding companies, each with a long-standing history and proven track record with some of the most challenging clinical trial outcomes – Central Nervous System (CNS) disorders.

MedAvante-ProPhase is proud to be a member of the WIRB-Copernicus Group, a family of companies dedicated to improving the quality and efficiency of clinical trials. Through its subsidiaries, WCG has served for nearly 50 years as the trusted partner and advisor to sponsors, contract research organizations, hospitals, health care systems, universities, and academic medical centers. Each WCG company has a unique history and holds one-of-a-kind credentials and experience. Together, we provide our clients with solutions that reflect new ways of thinking and operating in the clinical research industry. Learn more about WCG >

MedAvante and ProPhase pioneered ingenious solutions to some of pharma’s most intractable problems.

Both companies were founded more than a decade ago to address high failure rates of clinical trials of psychotropic drugs, the efficacy of which are measured with subjective ratings susceptible to biases, variability and error.

MedAvante pioneered Central Ratings, an unconventional solution built on the novel idea of having a small highly calibrated cohort of expert raters administer clinical outcome assessments remotely.

ProPhase became a global provider of measurement-related specialty solutions in clinical trials by focusing on optimizing the selection, use, and analysis of behavioral endpoints to mitigate trial risk and maximize the likelihood of study success.

As Central Ratings gained acceptance in large global studies, MedAvante replaced the paper-based rating scales its own clinicians were using by developing a digital platform to administer clinical outcome assessments (eCOA) and manage electronic source (eSource) data, starting in 2009.

Today’s generation of that technology innovation is the Virgil platform, used in clinical trials around the world to improve efficiency and quality at research sites while providing study sponsors with immediate access to high quality clinical trial data.

MedAvante-ProPhase is committed to continuing to bring digital innovation and scientific quality to the crucially important process of collecting, managing and analyzing clinical trial data. We will build on the great progress we’ve made improving signal detection in CNS studies to enable smarter, faster clinical trials in all therapeutic areas that will bring better treatments to the people who need them most.

Our Vision

We strive for smarter,
faster clinical trials.


Steven Herne

Chief Commercial Officer

Steve Herne, an experienced sales and business development executive in both technology and services, joined MedAvante-Prophase as Chief Commercial Officer in July 2017 with overall responsibility for sales and marketing.

Prior to his appointment, he was Chief Commercial Officer, eHealth Solutions at Bioclinica, a provider of clinical trial management solutions. Previously, he served as Chief Commercial Officer at clinical trial data and technology company ERT, and Senior Vice President, Global Business Development at Icon Development Solutions. Earlier, he was a Vice President at Covance in the United Kingdom, and a Senior Director at MDS Pharma Services.

Herne began his career as a Senior Research Scientist for Inveresk Research before moving to a business development position at Quintiles and then returned to Inveresk as Senior Business Development Manager.

Steven Downing

Chief Financial Officer

Steve Downing has more than 25 years of experience in finance and business.

Before joining MedAvante-ProPhase, Mr. Downing served as Executive Director of Finance for the Client Support Center of Excellence for Covance. In that position, he led the planning and implementation of a finance reorganization process. Mr. Downing also lent support to responsibility, strategy, capital investment, expansion and financial training. In addition, he led a team responsible for the overall financial health of projects, including profitability, revenue recognition, cash flow, invoicing, and financial training for project managers and their teams.

His previous roles at Covance included Global Controller for the Clinical Development Services Business and Senior Financial Analyst for the Corporate office. Before joining Covance, Mr. Downing worked as a Senior Consolidations Analyst with IMO Industries and as an auditor with KPMG Peat Marwick LLP.

Mr. Downing has a BS in Accounting and Finance from Trenton State College, and is a Certified Public Accountant.

Greg Barrett

Chief Technology Officer

Greg Barrett leads worldwide software and platform development for MedAvante-ProPhase, supporting clinical science and signal detection capabilities. He joined the company in April 2017, bringing 30 years of information technology experience.

Prior to his current position, Greg was Vice President of IT at the clinical research organization Covance, now a division of LabCorp Holdings. In his role as Global IT Leader for Covance, he oversaw 880 team members supporting five business units with applications, architecture, business engagement and computer systems validation. Before that post, Greg was VP of IT with responsibility for creating and leading Covance’s 400-member global applications and architecture organization, supporting 207 applications and serving all five business units.

Greg began his career at AT&T with technical staff assignments as a developer, analyst, architect, project lead and program manager. From there he moved to Computer Sciences Corporation as Director of IT, where he oversaw the development and maintenance arms of the 210-team member AT&T and 110-team member St. Vincent’s Medical Center accounts and supported other accounts including Sun Microsystems, Zurich Insurance, Delphi Automotive, Dunn & Bradstreet, and General Dynamics.

He holds a BS degree in Computer Science from Rutgers University and earned an MBA in Finance at Fairleigh Dickinson University.

Angela Wilmer

Vice President, Regulatory and Quality Assurance

Since joining MedAvante-ProPhase in 2002, Angela Wilmer has developed provider networks and managed both the Rater Operations and Human Resources departments. She executed the company’s first feasibility study using videoconferencing. As Vice President of Regulatory and Quality Assurance since 2008 she has been responsible for evaluating activities of regulatory significance and ensuring that quality standards and regulatory requirements are implemented and maintained throughout the organization while leading audit teams in successful completion of more than 60 customer audits without a single significant finding. Widely recognized for her achievements in organizational leadership, Ms. Wilmer is often sought for advice and collaboration and asked to share her expertise with professionals worldwide through networking and consulting.

Before joining MedAvante-ProPhase, Ms. Wilmer worked for more than 20 years in health care where she developed expertise in regulation interpretation. At Horizon Blue Cross Blue Shield of New Jersey, she successfully developed and managed health care policies and administrative procedures to ensure compliance with regulatory agencies and other standards for a network of over 10,000 providers. She has developed recruitment, contracting, and retention strategies for employees, physicians, and ancillary providers.

Ms. Wilmer has a BS in Management from the University of Phoenix and will obtain a BA in Professional Counseling from Liberty University in 2017.

Christopher Randolph, PhD

Chief Scientific Officer

Dr. Randolph has extensive experience in CNS clinical trials work, as an investigator, consultant and creator and supervisor of rater training programs for a large number of Phase II and Phase III multinational studies in Alzheimer’s disease and other neurodegenerative conditions; schizophrenia; stroke; hepatic encephalopathy; and traumatic brain injury.

He also has a strong background and interest in psychometrics and neurocognitive assessment, having worked for over 20 years as a consultant on test development, including the revisions of the Wechsler intelligence and memory scales. He is the author of the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS), a brief neurocognitive battery used widely around the world.

Dr. Randolph is Clinical Professor of Neurology and Director of the Neuropsychology service at Loyola University Medical Center and is board-certified in clinical neuropsychology. He has authored more than 90 peer-reviewed articles on a variety of research interests, including Alzheimer’s disease, Huntington’s disease, Parkinson’s disease, traumatic brain injury, sport-related concussion, Tourette’s syndrome, schizophrenia and hepatic encephalopathy.

Dr. Randolph received an undergraduate degree from Vanderbilt University, and MS and PhD degrees from Rutgers University/University of Medicine and Dentistry of New Jersey. He completed an Intramural Training Award fellowship at the Clinical Brain Disorders Branch of the NIMH, and worked as a senior staff fellow in the Experimental Therapeutics Branch of the NINDS.

Mike Cioffi

Senior Vice President, Clinical Operations

Mike Cioffi brings more than 20 years of pharmaceutical industry experience to his role leading MedAvante-ProPhase’s operational business units in support of project delivery and implementing global enterprise solutions that will drive continuous improvements in efficiency, output, and quality.

Before joining MedAvante-ProPhase in July 2017, he held the position External Clinical Innovation Leader at Roche, where he was responsible for developing, integrating and operationalizing strategic innovations throughout drug development. Prior to that post, he was Vice President, Project Management, Americas for the clinical research organization PRA HealthSciences, leading a team of clinical research professionals covering all therapeutic areas. He also held senior project management and operations posts at Worldwide Clinical Trials, Inc. and INC Research where he has been responsible for overall strategy and direction of global business units, most notably in the field of Central Nervous System (CNS).

Mr. Cioffi holds the B.S. degree in Biochemical Pharmacology from the State University of New York (SUNY) at Buffalo.

Janet B. W. Williams, PhD

Senior Vice President, Global Science

Dr. Williams has more than 30 years of clinical research experience in both industry and academia.

Before coming to MedAvante-ProPhase in 2007, she worked for 32 years in academic settings, including as Professor of Clinical Psychiatric Social Work in the Departments of Psychiatry and Neurology at Columbia University College of Physicians and Surgeons, and as Research Scientist and Deputy Chief of the Biometrics Research Department at the New York State Psychiatric Institute. She is now Professor Emerita at Columbia University.

Dr. Williams is well known in the field for her development of psychiatric classifications and instruments to measure psychopathology.

Dr. Williams has a BS in Biology from Tufts University, an MS in marine biology from the University of Massachusetts–Dartmouth, and an MS and PhD in social welfare from the Columbia University School of Social Work. She is the author of more than 240 scholarly publications and serves on the editorial boards of several psychiatric and social work journals. She has received numerous awards for her achievements and contributions in social work and psychiatry.

Kenneth A. Kobak

Senior Scientist

Dr. Kobak is a psychologist with more than 30 years of clinical research experience in both industry and university medical settings. Throughout his career, he has focused on clinical assessment, rater training, rating scale development and clinical trials methodology.

Prior to MedAvante-ProPhase, Dr. Kobak founded the consultancy Research Training Associates, where he developed new methodologies for training and calibrating raters in clinical trials using digital technologies.

At the University of Wisconsin Medical School and Healthcare Technology Systems, Dr. Kobak managed a clinical trials unit and pioneered the use of computer-administered rating scales in clinical trials. He authored computer-administered versions of several clinician-administered rating scales, including depression and anxiety scales that are widely used today, and a computer-administered version of the PRIME-MD, a diagnostic interview that was published in JAMA.

Dr. Kobak received his BA, MSSW, and PhD from the University of Wisconsin-Madison. He is co-author of the Rater Applied Performance Scale (RAPS), which is widely used to evaluate raters’ applied clinical skills in administering symptom rating scales, and is co-author with Dr. Janet Williams of the SIGMA, a structured interview guide for the Montgomery-Asberg Depression Rating Scale. Dr. Kobak received several NIMH grants to develop and study rater training methodology for depression, schizophrenia, and autism. He received a New Investigator Award from NIMH in 1996, and is a core member of the Depression Rating Scale Standardization Team (DRSST).

Selam Negash

Senior Scientist

Dr. Negash serves as the scientific lead bridging research and operations to ensure MedAvante-ProPhase clinical trial services are implemented successfully from a scientific and service delivery perspective. Prior to joining MedAvante-ProPhase, she was a Research Associate at the Penn Memory Center, a National Institute on Aging-designated Alzheimer’s Disease Center (ADC). Her work has focused on investigating factors associated with successful cognitive aging, including lifestyle factors such as cognitive activity, and on developing interventions that enhance cognitive fitness in older adults. She also studies successful cognitive aging in minority populations, particularly African-Americans. Her other area of work focuses on examining implicit and explicit learning and memory systems in healthy aging and in mild cognitive impairment.

She received her doctoral training in neuroscience from Georgetown University and completed her postdoctoral training in the Alzheimer’s Disease Research Center at Mayo Clinic Rochester, where she also earned the Master of Science degree in the Clinical Research Program.

Sofija Jovic, PhD, MBA

Business Transformation Advisor

Dr. Sofija Jovic is focused on the strategic combination of MedAvante-ProPhase as the thought leader in using measurement science and data quality to transform clinical trials. In her previous role of Chief Executive Officer of ProPhase, Dr. Jovic guided the transformation from a four-person start-up to a global industry leader in collaboration with ProPhase founder Dr. Mark Opler.

Dr. Jovic started her career as a clinical psychologist: teaching, conducting research and providing testing and treatment at a variety of treatment settings. Dr. Jovic has published in peer-reviewed journals and presented scientific papers at professional and industry conferences. She is a member of the American Psychological Association (APA), Anxiety Disorders Association of America (ADAA), The International Society for CNS Drug Development (ISCDD), The International Society for CNS Clinical Trials and Methodology (ISCTM), American Society for Clinical Psychopharmacology (ASCP) and is a founding member of CNS Summit.

Dr. Jovic earned her PhD in Clinical Psychology from Long Island University and her Master’s in Business Administration from Massachusetts Institute of Technology, Sloan School of Management.

Mark Opler, PhD, MPH

Chief Research Officer

Dr. Mark Opler serves as Chief Research Officer, directing scientific research and development at MedAvante-ProPhase. Dr. Opler was the founder of ProPhase and served as its CEO and Chief Scientific Officer among other positions. He holds the titles of Adjunct Assistant Professor of Psychiatry at New York University and Assistant Professor of Clinical Neuroscience at Columbia University’s College of Physicians and Surgeons. His academic research focuses on the etiology, phenomenology, and treatment of serious and persistent mental disorders. He is also leading the development of the new upcoming edition of the PANSS Manual©.

Dr. Opler is a former “NARSAD Young Investigator” recipient and has recently completed a 5-year research grant from the US NIH to establish an international cohort in Finland to investigate the role of paternal reproductive health in the onset of mental disorders. He has co-authored over 40 peer-reviewed publications and has contributed to multiple book chapters and review articles on schizophrenia and mental health research.

He received his BSc at SUNY Stony Brook and his MPH and PhD from Columbia University. He is also a graduate of the Psychiatric Epidemiology Training Program at Columbia University and completed his Postdoctoral Fellowship at the New York State Psychiatric Institute.

Jennifer Lord-Bessen, PhD

Vice President of Clinical Data Sciences

As Vice President of Clinical Data Sciences, Dr. Lord-Bessen oversees MedAvante-ProPhase Clinical Data Analytics services including data management, statistics, and psychometric activities, including consultation on the development and validation of new Clinician-Reported and Patient-Reported Outcomes as well as the conversion of existing assessments to electronic format.

Dr. Lord-Bessen has over twenty years of experience in statistics and measurement. Prior to joining ProPhase in 2015, she was a Research Scientist in the field of educational assessment, leading the standard setting program for CTB/McGraw Hill Education.

Dr. Lord-Bessen obtained a PhD in Psychometrics and Quantitative Psychology from Fordham University and MA in Educational Psychology from Teachers College, Columbia University. She completed a Predoctoral Fellowship at Memorial Sloan Kettering Cancer Center.

Scientific Advisory Boards

Recognized experts and key opinion leaders in various fields play a vital role in shaping and refining MedAvante-ProPhase solutions. Our Scientific Advisory Boards meet regularly to review research progress and recommend improvements for our methods and procedures.


Twelve board members from leading universities and research institutions provide counsel and guidance to MedAvante-ProPhase on initiatives relating to mood, anxiety, schizophrenia, and other psychiatric disorders.

Co-chaired by John M. Kane, MD, Chairman of the Department of Psychiatry at the Zucker Hillside Hospital and Professor of Psychiatry, Neurology and Neuroscience at the Albert Einstein College of Medicine, where he is the Dr. E. Richard Feinberg Chair in Schizophrenia Research.



Eight distinguished experts from leading American and European institutions engaged in neurocognition research guide the development of MedAvante-ProPhase signal detection solutions in Alzheimer’s disease, Parkinson’s disease and related neurodegenerative disorders.

MedAvante-ProPhase US/European Alzheimer’s advisory board is co-chaired by Jeffrey Cummings, MD, the Director of the Cleveland Clinic Lou Ruvo Center for Brain Health in Las Vegas, Nevada.


Our second Alzheimer’s advisory board guides the application of clinical trial solutions in Japan. Eleven top leaders from major Japanese universities and research institutions provide their expertise to enhance the ability to collect high-quality research data with less error and greater signal detection.

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MedAvante-ProPhase is always seeking talented people
to join our world-class team.

Got what it takes?

At MedAvante-ProPhase, we look for colleagues who combine talent with a powerful desire to change healthcare for the better and ensure that effective therapies make it to the patients who need them.

This is the mission uniting the clinicians, scientists, technologists, and operations experts whose mix of energy, inventiveness, and skill drives not only MedAvante-ProPhase but the entire WIRB-Copernicus Group (WCG) family of companies in a relentless quest to improve clinical trials.

Learn more about joining the MedAvante-ProPhase and WCG teams:

See All Open Positions


Client Services


What do you do at MedAvante-ProPhase?
As a member of the Business Development team, I am responsible for overseeing the creation of our responses to requests for information and proposals from drug development sponsors planning clinical trials. I also serve as a subject matter expert on clinical and technical aspects of our service solutions.

Why did you decide to work at MedAvante-ProPhase?
When MedAvante-ProPhase was looking to expand into the Alzheimer’s area with a focus on improving data quality, I found a great match with my background as Clinical Neuropsychologist and previous experience in rater training and quality control.

What do you like best about your job?
MedAvante-ProPhase lacks the layers of hierarchy that can kill good ideas or contributions from different departments, and our entire team is determined to stay on the forefront of signal detection and clinical trial technology.

What are your colleagues like?
Hard working, open and approachable.
They like to be challenged, and they constantly push the limits of their comfort zone to ensure that quality of service is the first thing any customer remembers. And we are each other’s safety net when push comes to shove.

What impact has working at MedAvante-ProPhase had on you?
I have been able to apply my clinical and operational background to a more business driven area, and I am able to help shape the image of MedAvante-ProPhase in the customer’s mind.


Clinical Trial Services


What do you do at MedAvante-ProPhase?
My job is to perform live clinical psychiatric interviews by phone and video conferencing with study subjects participating in clinical trials. I also review documents and recordings of neuropsychological and psychiatric assessments conducted by other clinicians to provide feedback on scoring and administration.

Why did you decide to work at MedAvante-ProPhase?
I found in MedAvante-ProPhase a great place to use my behavioral health experience in a clinical trials setting, as well as a perfect fit for my years of face-to-face counseling, neuropsychological assessments, and phone work at an employee assistance program provider.

What do you like best about your job?
I like the excellent training, as well as the opportunity to work with a dedicated group of professionals. I also greatly appreciate my manager’s skillset and guidance.

What are your colleagues like?
I have worked a number of places in my career before MedAvante-ProPhase but I never met a more caring and dedicated group of employees as I have here. While I work in the office, I feel just as connected to my peers who work remotely.

What impact has working at MedAvante-ProPhase had on you?
The learning at MedAvante-ProPhase for me started on day one, and has never stopped. As the company grows, so does my ability to gain further skills as a clinician and professional in different research areas.


Project Management


What do you do at MedAvante-ProPhase?
I am a member of a global team that’s the primary point of contact for clinical trial sponsors as well as principal investigators and study coordinators. I administer the adjudication process for large global studies by tracking cases, contacting sites for needed information, and assembling and storing the required documentation.

Why did you decide to work at MedAvante-ProPhase?
I come from the medical field, having graduated as a Medical Doctor in Dominican Republic. In MedAvante-ProPhase I’ve found a company is multicultural and gives me the opportunity to interact with other colleagues around the world.

What do you like best about your job?
I really love the flexibility that makes my work very convenient for me and my family. I also like the way our multicultural team all treats each other with respect and I enjoy working with colleagues from around the world.

What are your colleagues like?
In our department we are very diverse in culture, beliefs and opinions, but there is something common in all of us and that is the respect and the compassion we all have. My colleagues really care about each other and are willing to help and support.

What impact has working at MedAvante-ProPhase had on you?
Working here has helped me take personal responsibility for learning and development, and increased my understanding that there is a lot more to do in the pharma world.


Project Management


What do you do at MedAvante-ProPhase?
I interact with people from all over the world in my job, exchanging information, optimizing various processes, and, most importantly, providing high quality technical support and customer service to our clinical trial sites. The nature of our work is such that I am constantly learning new things, and I must steadily exercise and develop my skills.

Why did you decide to work at MedAvante-ProPhase?
When I first came across the MedAvante-ProPhase job opening, I knew the skills I had acquired during my career up to that point would make me a strong candidate. On the other hand, medical research was a completely new field for me. Therefore, the job was both a good fit and a big challenge for me. I had to apply.

What do you like best about your job?
Every day is interesting and challenging, it might be a bit hard, but it is never boring. I love being trusted to oversee and carry out projects with my co-workers. It makes me feel part of a team and boosts my confidence.

What are your colleagues like?
My colleagues are hardworking, bright and talented people. We work as a team. Each one of us tries our best to produce a collective result that is optimal for our company and for our clients. My co-workers have my back, as I have theirs. Therefore, a strong bond has developed between us.

What impact has working at MedAvante-ProPhase had on you?
I have acquired more skills in four years at MedAvante-ProPhase than in my entire previous career. My problem solving skills have improved and I have gained experience in productively interacting with people of very different professional or cultural backgrounds.


Clinical Trial Services


What do you do at MedAvante-ProPhase?
I have daily contact with clinical trial sites and sponsors of studies around the world, attending teleconferences with each of the study teams and training other clinicians both internally and at sites. I also track statistical data on my studies and resolve discrepancies and other clinical queries.

Why did you decide to work at MedAvante-ProPhase?
A graduate school classmate who worked for MedAvante-ProPhase told me about the company’s goal of improving clinical studies and I was excited to become a part of it. Everyone here has been incredibly supportive and collaborative.

What do you like best about your job?
I like having the opportunity to work with so many different people in so many different countries, not only our staff but also training people working on trials supported by our technology and services. I really appreciate the opportunity to travel, collaborating with and presenting to scientific leaders.

What are your colleagues like?
My colleagues are helpful and hardworking, and also very supportive. We truly have a team mentality and we all work to assist one another and elevate each other in any way possible. They are all very knowledgeable and experienced and are able to guide sites and sponsors when needed.

What impact has working at MedAvante-ProPhase had on you?
My job has allowed me to work with scientific experts and learn about new indications and scales. I have also learned much about study design and how to work within the different agencies and sites internationally.


Project Management


What do you do at MedAvante-ProPhase?
I am a senior project manager in Asia Pacific region, which means that I mainly take care of day-to-day project status and working very closely with the study sites. I am responsible for communicating with global study sponsors and an important part or my role is to confirm that our procedures match local culture.

Why did you decide to work at MedAvante-ProPhase?
The freedom of working style and an opportunity to help make the MedAvante-ProPhase reputation as a good vendor provider between the Japan sites and sponsors, an achievement that took me and our team many years and lot of time to achieve.

What do you like best about your job?
You are free to decide how you manage your own project, task, time, working style and which you can’t find in other companies.

What are your colleagues like?
We are a dream team. My colleagues like to help and support each other like a family and they are a part of my soul in my job.

What impact has working at MedAvante-ProPhase had on you?
Because MedAvante-ProPhase is a professional company specifically focused in the CNS therapeutic area, I have had the opportunity to become a CNS professional myself, unlike my past work in a CRO when I needed to work in many areas without that identity.




What do you do at MedAvante-ProPhase?
I am responsible for global infrastructure, support, and security so my work can be very challenging but also very rewarding. Some days it’s evaluating the right technology and solution to drive our company forward, others days are spent solving specific problems. Our goal is to support every customer – internal or external – with a smile while making infrastructure as seamless as possible.

Why did you decide to work at MedAvante-ProPhase?
The passion and drive that MedAvante-ProPhase has as a company is what drove me to join. During my interview I was really impressed with how perfectly the company aligned with what I was looking for.

What do you like best about your job?
I love technology, and I believe we have the opportunity to be on the cutting edge and continue investing in our future. We are a technology company that is really focused on making this world a better place by dramatically improving clinical trials.

What are your colleagues like?
We are a highly diverse company with a mixture of many cultures. I really like learning about people and their passion, and I feel lucky to work with some really great people who are passionate about what they do and driven to get results.

What impact has working at MedAvante-ProPhase had on you?
I would say that this opportunity has given me the ability to work with many large pharma companies, giving me a really great perspective of how much of a difference our products can make to clinical trials.


Clinical Trial Services


What do you do at MedAvante-ProPhase?
The main theme in my scientific career has been memory research and the enhancement effects of neurotrophic drugs like neuropeptides in patients with memory disturbances, and dementia. Since retiring from my university position as head of the Clinical Neuropsychology department, I have been working as a MedAvante-ProPhase trainer and clinician.

Why did you decide to work at MedAvante-ProPhase?
I decided to accept the invitation to work for MedAvante-ProPhase because I knew they share my belief that the lack of solid methodology, structured assessments and knowledge about statistical analyses has often biased the outcome of psychiatric and cognitive studies.

What do you like best about your job?
The company is focused on solid methodology, standardized training and calibration of clinicians and trainers. I value the opportunity to pass on my experience to people from different background and cultures.

What are your colleagues like?
Professional, enthusiastic, hardworking people. They try to improve and stimulate each other, and MedAvante-ProPhase indeed works hard to create an atmosphere of “belonging to the MedAvante-ProPhase family.”

What impact has working at MedAvante-ProPhase had on you?
I have been inspired by the opportunity to work with people from different background and cultures.


Project Management


What do you do at MedAvante-ProPhase?
I manage Project Services including Customer Support, Technical Support and Fulfillment. My day consists of problem solving, revamping processes and motivating a team of hardworking individuals. My goal each day is to leave the office knowing that I accomplished something within my department or added a thought that will inspire innovation.

Why did you decide to work at MedAvante-ProPhase?
I saw an opportunity to work with a growing company at the forefront of innovation in clinical research. I believe in MedAvante-ProPhase’s values and mission, and felt that I had a unique perspective to contribute to the company’s growth.

What do you like best about your job?
I like that my opinion counts and that I am able to contribute to products and processes that can revolutionize this industry. I am not a number here but a part of a family. Every day I get to add to the forward progress of an ever evolving industry.

What are your colleagues like?
My colleagues are my family, the most compassionate, ambitious, committed group of people. I find it inspiring to work with people who are passionate about what they do, consistently dedicating their time and energy to help bring effective therapies to people who need them.

What impact has working at MedAvante-ProPhase had on you?
Working at Medavante-ProPhase allows me to use my creative brain to engage and inspire people and I know my contribution means something. I can look at a product and say “Wow, I did that”. That’s allowing me to grow more confident as a manager with a strategic vision for this ever evolving industry.

Application Process

Please apply online See Open Positions with your CV and cover letter in English. Candidates for clinical positions may be asked to complete a Clinical Experience Questionnaire. After the CV screening, selected candidates will be contacted to schedule phone or Skype interviews.

We value your interest in MedAvante-ProPhase, try to review all submissions in a timely manner, and strives continuously to improve our application process and candidate experience.

Who we are

About Us

MedAvante-ProPhase is a leading global clinical data services company. Our offerings include the Virgil Investigative Study Platform and scientific risk-reduction services – including Rater Qualification and Certification, Independent Review and remote Independent Ratings – to support clinical trials of treatments for central nervous system (CNS) and other disorders.

MedAvante-ProPhase is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age or veteran status.

MedAvante-ProPhase offers competitive salary and comprehensive benefits to eligible employees.

See Open Positions

Our Locations

MedAvante-ProPhase corporate headquarters is located in Hamilton NJ, which is easily accessible via NJ Transit and within walking distance to the Hamilton train station. Our New York City office is situated in midtown Manhattan.

We serve global studies from our Munich office, established in 2011 within the MTZ technology centre, and our Tokyo office, situated near Senzoku station.

In addition, MedAvante-ProPhase employs remote, home-based employees and consultants in Bangladesh, Bulgaria, Canada, Czech Republic, Denmark, Finland, France, Germany, Hungary, Israel, Italy, Japan, Mexico, Netherlands, Norway, Poland, Portugal, Romania, Russia, South Korea, Spain, Turkey, United Kingdom, Ukraine and the United States.

See Open Positions

MedAvante’s Timeline


MedAvante breaks new ground with its Central Ratings methodology.


Building on its Central Ratings expertise, MedAvante pioneers eSource.


MedAvante expands to providing service in global trials.

First MedAvante-generated eSource data accepted by FDA as part of a successful drug approval.


FDA issues guidance encouraging the industry adoption of eSource solutions – which MedAvante has already been developing for five years.


MedAvante launches the Virgil Investigative Study Platform.


Milestone: Three and a half million pages of paper captured digitally by Virgil — without losing a single data point. If stacked, the pages would exceed the height of The Empire State Building.


Virgil continues to evolve with regular platform updates driven by site-based research and feedback.

MedAvante provides global services with native-language clinicians in over 40 countries.

We’re committed to providing the tools for smarter, faster clinical trials. With Virgil, the future looks even brighter.

MedAvante-ProPhase Worldwide